tRANSLATIONAL rESEARCH pROJECTS
The featured translational research projects underway at TRI are identified by their progress along our translational research pathway. As a research institute with an innovative approach to medical research, we are developing models based on the success of existing projects.
The translational pathway model allows us to see where research projects are at, and identify individual and common roadblocks to further progress. Each milestone, from T0 to T4, involves achieving significant progress towards answering a clinical question and a positive outcome for a patient.
t0 - Innovation driven by clinical question
To reach T0, a project must have been through a discovery phase to arrive at an innovation, which has been driven by a clinical question or patient need.
T1 - Clinical Study
The T1 milestone is reached when planned human studies meet ethical requirements. This phase may involve a small number of patients in a clinical trial.
T2 - Clinical trial
The T2 milestone involves expanded trials with more patients at a number of different locations. This phase often takes several years to ensure the discovery is beneficial and effective.
T3 - Clinical practice
T3 is reached when a discovery has been published, peer-reviewed, tested and proven successful to the extent that it is adopted into clinical practice.
T4 - international adoption and assessment
The T4 milestone is achieved once independent evaluation by organisations such as WHO has estabished a proven health benefit on a world-wide basis.
