Genomics
Genomic medicine research focuses on understanding the genetic causes of many common human diseases. Researchers at TRI are investigating how genomics can potentially be used to inform diagnosis, prognosis and treatment of diseases, including cancers.
Genomics in disease - A wide range of genomics research is underway at TRI, including the use of genomics to identify targets for osteoporosis intervention, relationships between birthweight and cardiometabolic risk, and other diseases including rheumatology and ankylosing spondylitis.
- An overview of genomics research from UQ's Frazer Institute, based at TRI, can be viewed here.
- The UQ Centre for Clinical Genomics, located at TRI, uses innovations in gene sequencing, genotyping and proteomic technologies to research a wide range of complex diseases, including cancer, arthritis, osteoporosis, diabetes, eczema and other chronic diseases.
Genomics diagnostic service - The QUT Australian Translational Genomics Centre (ATCG) is affiliated with TRI and based at the PA Hospital, as the first genomics diagnostic service in Queensland. The facility offers rapid and comprehensive screening for cancer mutations, identifying specific mutational profiles at diagnosis required to inform whether they are suitable for treatment with certain medications. Read more.
Microbial biology and metagenomics - Professor Mark Morrison and his team are using DNA sequencing technologies to produce new insights into the microbiome. They aim to improve methods for monitoring and adjusting the gut microbiota to improve and maintain health, and better diagnose and treat disease. Read more.