Dr Nathalie Bock

Book Chapters

• Bock N* - Tissue-Engineered Models of the Metastatic Human Bone Microenvironment In Vitro: A Novel Theranostics Platform for Cancer Research in 3D. Methods in Molecular Biology (2019) Springer Nature. Book series: Theranostics
• Bock N* and Röhl J - Real Time 3D Quantification of Metastatic Cancer: Exploiting an In Vitro Engineered Human Bone-Like Microenvironment. Methods in Molecular Biology (2019) Springer Nature. Book series: Theranostics

Reviews

• Vigata M, Meinert C, Hutmacher DW, Bock N*, Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques. Pharmaceutics 12-12 (2020). IF: 6.5, Q1 in Pharmacology and Pharmacy
• Bray LJ, Hutmacher DW, Bock N* - Addressing Patient Specificity in the Engineering of Tumor Models. Frontiers in Bioengineering and Biotechnology. 7:217 (2019).  IF: 6.0, Q1 Multidisciplinary Sciences
• Bock N*, Dargaville TR, Woodruff MA. Electrospraying of Polymers with Therapeutic Molecules: State of the Art. Progress in Polymer Science 37-11 (2012) p.1510-1551. IF 31.3, Leading Journal in Polymer Science
• Blackwood KA, Bock N (co-first author), Dargaville TR, Woodruff MA. Scaffolds for Growth Factor Delivery as Applied to Bone Tissue Engineering. International Journal of Polymer Science (2012) art. no. 174942. IF 3.0, Q3 in Polymer Science

Research Articles

First or senior author (including co-first and co-senior authorships)

• Laubach M*, Herath B, Suresh S, Saifzadeh S, Dargaville BL, Cometta S, Schemenz V, Wille ML, McGovern J, Hutmacher DW, Medeiros Savi M*, Bock N*. An innovative intramedullary bone graft harvesting concept as a fundamental component of scaffold-guided bone regeneration: A preclinical in vivo validation. Journal of orthopaedic translation. Accepted (2024). IF: 6.6, Q1 in Orthopaedics
• Bessot A, Gunter J, Waugh D, Clements JA, Hutmacher DW, McGovern J, Bock N*. GelMA and biomimetic culture allow the engineering of mineralized, adipose and tumor tissue human microenvironments for the study of advanced prostate cancer in vitro and in vivo. Advanced Healthcare Materials 2201701 (2023). IF: 11.0, Q1 in Engineering, Biomedical
• Bock N*, Forouz F, Hipwood L, Clegg J, Jeffery P, Gough M, van Wyngaard T, Pyke C, Adams M, Bray L, Croft L, Thompson E, Kryza T, Meinert C. GelMA, click-chemistry gelatin and bioprinted polyethylene glycol-based hydrogels as 3D ex vivo drug testing platforms for patient-derived breast cancer organoids. Pharmaceutics 15-1, 261 (2023). IF: 6.5, Q1 in Pharmacology & Pharmacy
• Hipwood L, Clegg J, Weekes A, Davern J, Dargaville T, Meinert*, Bock N*. Semi-synthetic click-gelatin hydrogels as tunable platforms for 3D cancer cell culture. Gels 8-12 (2022) IF: 4.4, Q1 in Polymer Science
• Bock N, Kryza T, Shokoohmand A, Rohl J, Ravichandran A, Wille M-L, Nelson CC, Hutmacher DW. In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer. Science Advances 7-27 (2021). IF: 14.5, Q1 in Multidisciplinary Sciences
• Vigata M, O’Connell CD, Cometta S, Hutmacher DW, Meinert C*, Bock N*, Gelatin methacryloyl hydrogels for the localized delivery of cefazolin. Polymers 13-22 (2021). *shared co-senior authors. IF: 5.0, Q1 Polymer Science
• Ravichandran A, Meinert C, Bas O, Hutmacher DW, Bock N*, Engineering a 3D bone marrow adipose composite tissue loading model suitable for studying mechanobiological questions. Materials Science & Engineering C 128 (2021). IF: 8.5, Q1 in Materials Science, Biomaterials
• Vigata M, Meinert C*, Pahoff S, Bock N*, Hutmacher DW*. Gelatin Methacryloyl Hydrogels Control the Localized Delivery of Albumin-Bound Paclitaxel. Polymers 12-2 (2020). *shared co-senior authors. IF: 5.0, Q1 Polymer Science
• Shokoohmand A, Ren J, Baldwin J, Atack A, Shafiee A, Theodoropoulos C, Wille ML, Tran P, Bray LJ, Smith D, Chetty N, Pollock PM, Hutmacher DW, Clements JA, Williams ED, Bock N*. Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts. Biomaterials 220 (2019). IF: 15.3, Q1 Materials Science, Biomaterials
• Bock N, Shokoohmand A, Kryza T, Röhl J, Meijer J, Tran PA, Nelson CC, Clements JA, Hutmacher DW. Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment. Bone Research 7-1 (2019). IF: 13.3, Q1 Cell & Tissue Engineering
• Bock N, Pham TLB, Nguyen TB, Nguyen TB, Tran HA, Tran PA. Polydopamine coating of uncrosslinked chitosan as an acellular scaffold for full thickness skin grafts. Carbohydrate Polymers 245 (2019). IF: 10.7, Q1 Chemistry, Applied
• Bock N*, Dargaville TR, Kirby GTS, Hutmacher DW, Woodruff MA. Growth-Factor Loaded Microparticle for Tissue Engineering: The Discrepancies of In Vitro Characterization Assays. Tissue Engineering, Part C – Methods 22-2 (2016). IF: 3.3, Q2 Materials Science, Biomaterials
• Bock N*, Woodruff MA, Dargaville TR. Controlling Microencapsulation and Release of Micronized Proteins using Poly(Ethylene Glycol) and Electrospraying. European Journal of Pharmaceutics and Biopharmaceutics 87-2 (2014) p.366-377. IF: 4.7, Q1 Pharmacology & Pharmacy
• Bock N*, Woodruff MA, Steck R, Hutmacher DW, Farrugia BL, Dargaville TR. Composites for Delivery of Therapeutics: Combining Melt Electrospun Scaffolds with Loaded Electrosprayed Microparticles. Macromolecular Bioscience 14-2 (2014) p.202-2014. IF: 2.9, Q1 Polymer Science
• Bock N*, Woodruff MA, Hutmacher DW, Dargaville TR. Electrospraying, a Reproducible Method for Production of Polymeric Microspheres for Biomedical Applications. Polymers 3-1 (2010) p.131-149, IF: 5.0, Q1 Polymer Science - Polymers Best Paper Award, 2nd prize.
• Bock N*, Riminucci A, Dionigi C, Russo A, Tampieri A, Landi E, Goranov VA, Marcacci M, Dediu V. A Novel Route in Bone Tissue Engineering: Magnetic Biomimetic Scaffolds. Acta Biomaterialia 6-3 (2010) p.786-896. IF: 10.6, Q1 Biomedical Engineering and Materials Science, Biomaterials

Co-authors

• Brennen NW, Le Magnen C, Karkampouna S, Anselmino N, Bock N, Choo N, Clark AK, Coleman IM, Dolgos R, Ferguson AM, Goode D, Krutihof-de Julio M, Navone NM, Nelson PE, O’Neill E, Porter LH, Ranasinghe W, Sunada T, Williams ED, Butker LM, Corey E, van Weerden WM, Taylor RA, Risbridger GP, Lawrence MG. Defining the challenges and opportunities for using patient-derived models in prostate cancer research. The Prostate (2024) IF: 2.8, Q2 in Urology & Nephrology
• Laubach M, Bessot A, McGovern J, Saifzadeh S, Gospos J, Segina DN, Kobbe P, Hildebrand F, Wille ML, Bock N, Hutmacher DW. An in vivo study to investigate an original intramedullary bone graft harvesting technology. European Journal of Medical Research (2023) IF: 4.2, Q2 in Medicine, Research & Experimental
• Laubach M, Herath B, Bock N, Suresh S, Saifzadeh S, Dargaville BL, McGovern J, Wille ML, Hutmacher DW, Medeiros Savi F. In vivo characterization of 3D-printed polycaprolactone-hydroxyapatite scaffolds with Voronoi design to advance the concept of scaffold-guided bone regeneration. Frontiers in Bioengineering and Biotechnology (2023) IF: 6.0, Q1 Multidisciplinary Sciences
• Kahl M, Schneidereit D, Meinert C, Bock N, Hutmacher DW, Friedrich O. A fluorescence-based opto-mechatronic screening module (OMSM) for automated 3D cell culture workflows. Biosensors and Bioelectronics: X, 100372 (2023) IF: 12.5, Q1 in Biophysics
• Cometta S, Jones RT, Juárez-Saldivar A, Donose BC, Yasir M, Bock N, Dargaville TR, Bertling K, Brunig M, Rakic AD, Willcox M, Hutmacher DW. Melimine-Modified 3D-Printed Polycaprolactone Scaffolds for the Prevention of Biofilm-Related Biomaterial Infections. ACS Nano 16-10 (2022) IF: 18.0, Q1 in Chemistry, Multidisciplinary
• Eggert S, Melanie Kahl, Bock N, Meinert C, Friedrich O & Hutmacher DW. An open-source technology platform to increase reproducibility and enable high-throughput production of tailorable gelatin methacryloyl (GelMA) – based hydrogels. Materials & Design 204 (2021) IF: 9.4, Q1 Materials Science, Multidisciplinary
• Cometta S, Bock N, Suresh S, Dargaville TR, Hutmacher DW. Antibacterial albumin-tannic acid coatings for scaffold-guided breast reconstruction. Frontiers in Bioengineering and Biotechnology 9:235 (2021). IF: 6.0, Q1 Multidisciplinary Sciences
• McGovern J, Bock N, Shafiee S, Martine L, Wagner F, Baldwin J, Landgraf M, Lahr C, Meinert C, Williams ED, Pollock PM, Denham J, Russell PJ, Risbridger GP, Clements JA, Loessner D, Holzapfel B, Hutmacher DW. A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells. Communications Biology 4-1 (2021) IF: 6.5, Q1 Biology
• Vigata M, Meinert C, Bock N, Dargaville BL, Hutmacher DW, Deciphering the molecular mechanism of water interaction with gelatin methacryloyl hydrogels: Role of ionic strength, pH, drug loading and hydrogel network characteristics. Biomedicines 9-5 (2021). IF: 4.8, Q2 Biochemistry & Molecular Biology
• Kahl M, Schneidereit, Bock N, Friedrich, Hutmacher DW, Meinert C, MechAnalyze: An Algorithm for Standardization and Automation of Compression Test Analysis. Tissue Engineering Part C: Methods 27-10 (2021). IF: 3.3, Q2 Materials Science, Biomaterials
• Lovell S, Zhang L, Kryza T, Neodo A, Bock N, De Vita E, Williams ED, Engelsberger E, Xu C, Bakker AT, Maneiro M, Tanaka RJ, Bevan CL, Clements JA, Tate EW. A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer. Journal of American Chemical Society 143-23 (2021). IF: 16.4, Q1 Chemistry, Multidisciplinary
• Murari G, Bock N, Zhou H, Yang L, Liew T, Fox K, Tran PA. Effects of polydopamine coatings on nucleation modes of surface mineralization from simulated body fluid. Scientific Reports 10-1 (2020) IF: 5.0, Q1 Multidisciplinary Sciences
• Vaquette C, Bock N, Tran P. Layered antimicrobial selenium nanoparticle–calcium phosphate coating on 3D printed scaffolds enhanced bone formation in critical size defects. ACS Applied Materials & Interfaces 12-50 (2020). IF: 10.4, Q1 Materials Science, Multidisciplinary
• Eggert S Kahl M, Kent R, Bock N, Meinert, Hutmacher DW. An open source technology platform to manufacture hydrogel-based 3D culture models in an automated and standardized fashion. JOVE-Journal of Visualized of Experiments e61261. IF: 1.4, Q3 Multidisciplinary Sciences
• Tran PA, O'Brien-Simpson N, Palmer JA, Bock N, Reynolds EC, Webster TJ, Deva A, Morrison WA, O'Connor AJ. Selenium nanoparticles as anti-infective implant coatings for trauma orthopedics against methicillin-resistant Staphylococcus aureus and epidermidis: in vitro and in vivo assessment. International Journal of Nanomedicine 14 (2019) 4613-4624. IF: 4.5, Q1 Pharmacology & Pharmacy
• Kryza T, Bock N, Lovell S, Rockstroh A, Lehman ML, Lesner A, Panchadsaram J, Silva LM, Srinivasan S, Snell CE, Williams ED, Fazli L, Gleave M, Batra J, Nelson C, Tate EW, Harris J, Hooper JD, Clements JA. The molecular function of kallikrein related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer. Molecular Oncology 14-1 (2019) IF: 7.4, Q1 Oncology
• Park JR, Van Guyse JFR, Podevyn A, Bolle E, Bock N, Linde E, Celina M, Hoogenboom R, Dargaville TR. Influence of side-chain length on long-term release kinetics from poly(2-oxazoline)-drug conjugate networks. European Polymer Journal 120 (2019) 109217. IF: 3.6, Q1 Polymer Science
• Kryza T, Silva LM, Bock N, Fuhrman-Luck R, Stephens C, Gao J, Samaratunga H, Lawrence M, Hooper JD, Dong Y, Risbridger G, Clements JA, Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells. Molecular Oncology 11-10 (2017) p.1307-1329.  IF: 7.4, Q1 in Oncology
• Panseri S, Russo A, Giavaresi G, Sartori M, Veronesi F, Fini M, Salter DM, Ortolani A, Strazzari A, Visani A, Dionigi C, Bock N, Sandri M, Tampieri A, Marcacci M. Innovative Magnetic Scaffolds for Orthopedic Tissue Engineering. Journal of Biomedical Materials Research – Part A 100A-9 (2012) p.2278-2286. IF: 3.2, Q2 Engineering, Biomedical, Citations: 39
• Riminucci A, Dionigi C, Pernechele P, De Pasquale G, De Caro T, Maria Ingo G, Mezzadri F, Bock N, Solzi M, Padeletti G, Sandri M, Tampieri A, Dediu VA. Magnetic and Morphological Properties of Ferrofluid-Impregnated Hydroxyapatite-Collagen Scaffolds for Bone Tissue Regeneration. Science of Advanced Materials 6-12 (2014) p.2679-2687.  IF: 1.2, Q4 Applied Physics
• Ristovski N, Bock N, Liao S, Powell S, Ren J, Kirby GTS, Blackwood KA, Woodruff MA. Improved fabrication of melt electrospun tissue engineering scaffolds using direct writing and advanced electric field control. Biointerphases 10-1 (2015). IF: 2.0, Q3 Biophysics

Impact factors (IF) in 2024, * = corresponding author