OVERVIEW

Gastroenterology and Hepatology

The TRI has a strong research program into gastrointestinal and liver disease in collaboration with clinicians at the Princess Alexandra Hospital and other partners such as the Mater Medical Research Institute/Mater Hospital.

This research program brings together researchers, scientists and clinicians to better understand the pathophysiology of a range of gastrointestinal and liver diseases aiming to prevent or more effectively treat highly prevalent disorders of the digestive tract. 

Find out more about these research programs below, which are being undertaken in collaboration with associated investigators from the Princess Alexandra Hospital and other partners such as the Mater Medical Research Institute/Mater Hospital. 


Resources 

Use of the sheathed (Brisbane Aseptic Biopsy Device) or standard biopsy devices to obtain gastrointestinal biopsies to characterise mucosal bacterial colonisation

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Nutrient challenge test

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Intestinal permeability test

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Measuring bacterial density on biopsy samples using qPCR

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Hydrogen breath test for small intestinal bacterial overgrowth (SIBO) using glucose

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Liver function breath test 13C with methacetin

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Pancreatic function breath test 13C with mixed triglyceride

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Helicobacter pylori 13C urea breath test

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Gastric Emptying 13C Breath Test (Substrate: 13C Octanoic Acid for Solid GE)

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DNA extraction from mucosal tissue

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Illumina Sequencing Library Prep

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Key Researchers
 
Graeme Macdonald
Gerald Holtmann
Ingrid Joy Hickman
Mark Morrison
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GASTROENTEROLOGY AND HEPATOLOGY RESEARCH PROGRAMS
Click a program below to learn more
 
Gastrointestinal Disease
Liver Disease
Microbial Biology and Metagenomics
Microbiome Translating innovation Program We now know that interactions between microorganisms that live on and inside our bodies can interact with our genes, and are affected by the environment we...Read more

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