OVERVIEW

Gastroenterology and Hepatology

The TRI has a strong research program into gastrointestinal and liver disease in collaboration with clinicians at the Princess Alexandra Hospital and other partners such as the Mater Medical Research Institute/Mater Hospital.

This research program brings together researchers, scientists and clinicians to better understand the pathophysiology of a range of gastrointestinal and liver diseases aiming to prevent or more effectively treat highly prevalent disorders of the digestive tract. 

Find out more about these research programs below, which are being undertaken in collaboration with associated investigators from the Princess Alexandra Hospital and other partners such as the Mater Medical Research Institute/Mater Hospital. 


Resources 

Use of the sheathed (Brisbane Aseptic Biopsy Device) or standard biopsy devices to obtain gastrointestinal biopsies to characterise mucosal bacterial colonisation

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Nutrient challenge test

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Intestinal permeability test

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Measuring bacterial density on biopsy samples using qPCR

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Hydrogen breath test for small intestinal bacterial overgrowth (SIBO) using glucose

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Liver function breath test 13C with methacetin

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Pancreatic function breath test 13C with mixed triglyceride

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Helicobacter pylori 13C urea breath test

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Gastric Emptying 13C Breath Test (Substrate: 13C Octanoic Acid for Solid GE)

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DNA extraction from mucosal tissue

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Illumina Sequencing Library Prep

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Key Researchers
 
Graeme Macdonald
Gerald Holtmann
Ingrid Joy Hickman
Mark Morrison
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GASTROENTEROLOGY AND HEPATOLOGY RESEARCH PROGRAMS
Click a program below to learn more
 
Gastrointestinal Disease
Liver Disease
Microbial Biology and Metagenomics
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International Clinical Trials Day: Q and A with TRI’s Steve Turner On International Clinical Trials Day on 20 May, we honour the incredibly hardworking professionals in the clinical trials...Read more
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Centre of Research Excellence in Digestive Health to improve outcomes for chronic digestive disorders With unexplained gastrointestinal (GI) symptoms a common and costly burden for many Australians,...Read more
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An arsenal of proteins used by many cell types to communicate with and control other cells could hold the answers to treating a multitude of diseases, especially cancer. The University of Queensland...Read more
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Growth hormone plays a key role in reducing inflammation and increasing survival rates following liver surgery. TRI-based researchers at The University of Queensland Diamantina Institute investigated...Read more
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A new spin-out from The University of Queensland (UQ) will develop a novel therapy for the growing problem of obesity-related liver disease with the support of an initial investment from IP Group...Read more
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Gut reaction linked to type 1 diabetes Source: UQ News, 13 August 2018 Understanding the link between diabetes and the gut could lead to the development of new therapies to delay the onset of type 1...Read more
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2018 ASMR Queensland Health & Medical Research Awards are now open The Australian Society for Medical Research (ASMR) have opened the 2018 Queensland Health & Medical Research Awards. These...Read more
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Kidney Health Week 2018 Kidney Health Week starts from March 5 to 11. It is to raise awareness of kidney disease and Kidney Health® Australia encourages everyone to learn more about the risk...Read more
Event
CONTEMPORARY AND EMERGING APPROACHES FOR THE MANAGEMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS Department of Gastroenterology & Hepatology at the Princess Alexandra Hospital presents this...Read more
TRANSLATING INNOVATION PROGRAMS Translating Innovation Programs are a collection of related projects based at TRI which involve collaboration across institutes, technologies and disciplines, united...Read more

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